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Identifying noncoding risk variants using disease-relevant gene regulatory networks
Identifying noncoding risk variants remains a challenging task. Because noncoding variants exert their effects in the context of a gene regulatory network (GRN), we hypothesize that explicit use of disease-relevant GRNs can significantly improve the inference accuracy of noncoding risk variants. We...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816022/ https://ncbi.nlm.nih.gov/pubmed/29453388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03133-y |
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