Distinct contribution of PD-L1 suppression by spatial expression of PD-L1 on tumor and non-tumor cells

Programmed cell death receptor 1 (PD-1) and its ligand, PD-L1, are important immune checkpoint proteins. Although antibodies that block PD-1/PD-L1 have shown promising clinical efficacy in a subset of cancer patients, the detailed cellular and molecular mechanisms behind anti-PD-1 and anti-PD-L1 imm...

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Detaylı Bibliyografya
Yayımlandı:Cell Mol Immunol
Asıl Yazarlar: Zhang, Xiaoqing, Cheng, Chen, Hou, Jiyan, Qi, Xinyue, Wang, Xin, Han, Ping, Yang, Xuanming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461875/
https://ncbi.nlm.nih.gov/pubmed/29568117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0021-3
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