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Temporally-Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

Antibody blockade of Programmed Death-1 (PD-1) or its ligand, PD-L1, has led to unprecedented therapeutic responses in certain tumor-bearing individuals, but PD-L1 expression’s prognostic value in stratifying cancer patients for such treatment remains unclear. Reports conflict on the significance of...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Noguchi, Takuro, Ward, Jeffrey P., Gubin, Matthew M., Arthur, Cora D., Lee, Sang Hun, Hundal, Jasreet, Selby, Mark J., Graziano, Robert F., Mardis, Elaine R., Korman, Alan J., Schreiber, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510474/
https://ncbi.nlm.nih.gov/pubmed/28073774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0391
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