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Distinct contribution of PD-L1 suppression by spatial expression of PD-L1 on tumor and non-tumor cells
Programmed cell death receptor 1 (PD-1) and its ligand, PD-L1, are important immune checkpoint proteins. Although antibodies that block PD-1/PD-L1 have shown promising clinical efficacy in a subset of cancer patients, the detailed cellular and molecular mechanisms behind anti-PD-1 and anti-PD-L1 imm...
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| Publicado no: | Cell Mol Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461875/ https://ncbi.nlm.nih.gov/pubmed/29568117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-018-0021-3 |
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