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Structures of the human spliceosomes before and after release of the ligated exon
Pre-mRNA splicing is executed by the spliceosome, which has eight major functional states each with distinct composition. Five of these eight human spliceosomal complexes, all preceding exon ligation, have been structurally characterized. In this study, we report the cryo-electron microscopy structu...
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| Publicat a: | Cell Res |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461851/ https://ncbi.nlm.nih.gov/pubmed/30728453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0143-x |
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