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Structures of the human pre-catalytic spliceosome and its precursor spliceosome

The pre-catalytic spliceosome (B complex) is preceded by its precursor spliceosome (pre-B complex) and followed by the activated spliceosome (B(act) complex). The pre-B-to-B and B-to-B(act) transitions are driven by the ATPase/helicases Prp28 and Brr2, respectively. In this study, we report the cryo...

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Detalles Bibliográficos
Publicado en:Cell Res
Main Authors: Zhan, Xiechao, Yan, Chuangye, Zhang, Xiaofeng, Lei, Jianlin, Shi, Yigong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274647/
https://ncbi.nlm.nih.gov/pubmed/30315277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0094-7
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