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Structure of a pre-catalytic spliceosome
Intron removal requires assembly of the spliceosome on pre-mRNA and extensive remodelling to form the spliceosome’s catalytic centre. Here we report the cryo-electron microscopy structure of the yeast pre-catalytic B complex spliceosome at near-atomic resolution. The mobile U2 snRNP associates with...
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| Publicado no: | Nature |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5503131/ https://ncbi.nlm.nih.gov/pubmed/28530653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22799 |
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