High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases

BACKGROUND: Patients with borderline resectable colorectal liver metastases (CRLM) frequently receive neoadjuvant chemotherapy (NC) to reduce tumour burden, thus making surgical resection feasible. Even though NC can induce severe liver injury, most studies investigating tissue-based prognostic mark...

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Vydáno v:Br J Cancer
Hlavní autoři: Strowitzki, Moritz J., Radhakrishnan, Praveen, Pavicevic, Sandra, Scheer, Jana, Kimmer, Gwendolyn, Ritter, Alina S., Tuffs, Christopher, Volz, Claudia, Vondran, Florian, Harnoss, Jonathan M., Klose, Johannes, Schmidt, Thomas, Schneider, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461828/
https://ncbi.nlm.nih.gov/pubmed/30808993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0406-9
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