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Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) and cancer stem cells (CSCs) are two important cellular components in the tumor microenvironment, which may modify the cancer phenotype and affect patient survival. However, the crosstalk between MDSCs and multiple myeloma stem cells (MMSCs) are r...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ai, Lisha, Mu, Shidai, Sun, Chunyan, Fan, Fengjuan, Yan, Han, Qin, You, Cui, Guohui, Wang, Yadan, Guo, Tao, Mei, Heng, Wang, Huafang, Hu, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461814/
https://ncbi.nlm.nih.gov/pubmed/30979371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1011-5
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