Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) and cancer stem cells (CSCs) are two important cellular components in the tumor microenvironment, which may modify the cancer phenotype and affect patient survival. However, the crosstalk between MDSCs and multiple myeloma stem cells (MMSCs) are r...

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Publicat a:Mol Cancer
Autors principals: Ai, Lisha, Mu, Shidai, Sun, Chunyan, Fan, Fengjuan, Yan, Han, Qin, You, Cui, Guohui, Wang, Yadan, Guo, Tao, Mei, Heng, Wang, Huafang, Hu, Yu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461814/
https://ncbi.nlm.nih.gov/pubmed/30979371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1011-5
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