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Therapeutic strategies targeting connexins

The connexin family of channel forming proteins are present in every tissue type in the human anatomy. Connexins are best known for forming clustered intercellular channels, structurally known as gap junctions, where they serve to exchange members of the metabolome between adjacent cells. In their s...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Laird, Dale W., Lampe, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461534/
https://ncbi.nlm.nih.gov/pubmed/30310236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2018.138
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