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Therapeutic strategies targeting connexins

The connexin family of channel forming proteins are present in every tissue type in the human anatomy. Connexins are best known for forming clustered intercellular channels, structurally known as gap junctions, where they serve to exchange members of the metabolome between adjacent cells. In their s...

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Pubblicato in:Nat Rev Drug Discov
Autori principali: Laird, Dale W., Lampe, Paul D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461534/
https://ncbi.nlm.nih.gov/pubmed/30310236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2018.138
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