Hepatic Autophagy Deficiency Compromises FXR Functionality and Causes Cholestatic Injury

Autophagy is important for hepatic homeostasis, nutrient regeneration and organelle quality control. We investigated the mechanisms by which liver injury occurred in the absence of autophagy function. We found that mice deficient in autophagy due to the lack of Atg7 or Atg5, key autophagy-related ge...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Khambu, Bilon, Li, Tiangang, Yan, Shengmin, Yu, Changshun, Chen, Xiaoyun, Goheen, Michael, Li, Yong, Lin, Jingmei, Cummings, Oscar W., Lee, Youngmin A., Friedman, Scott, Dong, Zheng, Feng, Gen-Sheng, Wu, Shangwei, Yin, Xiao-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461497/
https://ncbi.nlm.nih.gov/pubmed/30520052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30407
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados