Hepatic Autophagy Deficiency Remodels Gut Microbiota for Adaptive Protection via FGF15-FGFR4 Signaling

BACKGROUND & AIMS: The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver homeostasis, but the impact of hepatic autophagy...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Yan, Shengmin, Khambu, Bilon, Chen, Xiaoyun, Dong, Zheng, Guo, Grace, Yin, Xiao-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898036/
https://ncbi.nlm.nih.gov/pubmed/33127558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.10.011
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