Hepatic Autophagy Deficiency Remodels Gut Microbiota for Adaptive Protection via FGF15-FGFR4 Signaling

BACKGROUND & AIMS: The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver homeostasis, but the impact of hepatic autophagy...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Mol Gastroenterol Hepatol
Autori principali: Yan, Shengmin, Khambu, Bilon, Chen, Xiaoyun, Dong, Zheng, Guo, Grace, Yin, Xiao-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898036/
https://ncbi.nlm.nih.gov/pubmed/33127558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.10.011
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