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Targeted disruption of glycogen synthase kinase-3β in cardiomyocytes attenuates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice

Type 1 diabetic Akita mice develop severe cardiac parasympathetic dysfunction that we have previously demonstrated is due at least in part to an abnormality in the response of the end organ to parasympathetic stimulation. Specifically, we had shown that hypoinsulinemia in the diabetic heart results...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Zhang, Yali, Welzig, Charles M., Haburcak, Marian, Wang, Bo, Aronovitz, Mark, Blanton, Robert M., Park, Ho-Jin, Force, Thomas, Noujaim, Sami, Galper, Jonas B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461277/
https://ncbi.nlm.nih.gov/pubmed/30978208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215213
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