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Role of SREBP-1 in the Development of Parasympathetic Dysfunction in the Hearts of Type I Diabetic Akita Mice
Diabetic Autonomic Neuropathy (DAN), a major complication of diabetes mellitus, is characterized in part by impaired cardiac parasympathetic responsiveness. Parasympathetic stimulation of the heart involves activation of an acetylcholine-gated K(+) current, I(KAch), via a (GIRK1)(2)/(GIRK4)(2) K(+)...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2730600/ https://ncbi.nlm.nih.gov/pubmed/19423844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.193995 |
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