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Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response

BACKGROUND: Although constipation has been researched in various neurological disorders, including Parkinson’s disease (PD) and spinal cord injury (SCI), the pathological mechanism of this symptom has not been investigated in Alzheimer’s disease (AD) associated with loss of nerve cells in the brain....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Ji Eun, Park, Jin Ju, Lee, Mi Rim, Choi, Jun Young, Song, Bo Ram, Park, Ji Won, Kang, Mi Ju, Son, Hong Joo, Hong, Jin Tae, Hwang, Dae Youn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461235/
https://ncbi.nlm.nih.gov/pubmed/30978260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215205
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