Uridine stimulate laxative effect in the loperamide-induced constipation of SD rats through regulation of the mAChRs signaling pathway and mucin secretion

BACKGROUND: Uridine (Urd), which has been reported as a major component of RNA, plays an important role in various biological process including neuroprotection, biochemical modulation and glycolysis, although its role in constipation has yet to be established. Therefore, in this study, we investigat...

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Опубликовано в: :BMC Gastroenterol
Главные авторы: Kim, Ji Eun, Go, Jun, Sung, Ji Eun, Lee, Hyun Ah, Yun, Woo Bin, Hong, Jin Tae, Hwang, Dae Youn
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267432/
https://ncbi.nlm.nih.gov/pubmed/28122499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-017-0576-y
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