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Constipation in Tg2576 mice model for Alzheimer’s disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response

BACKGROUND: Although constipation has been researched in various neurological disorders, including Parkinson’s disease (PD) and spinal cord injury (SCI), the pathological mechanism of this symptom has not been investigated in Alzheimer’s disease (AD) associated with loss of nerve cells in the brain....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Kim, Ji Eun, Park, Jin Ju, Lee, Mi Rim, Choi, Jun Young, Song, Bo Ram, Park, Ji Won, Kang, Mi Ju, Son, Hong Joo, Hong, Jin Tae, Hwang, Dae Youn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461235/
https://ncbi.nlm.nih.gov/pubmed/30978260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215205
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