A novel tricarbonylmethane agent (CMC2.24) reduces human pancreatic tumor growth in mice by targeting Ras

Pancreatic Cancer (PC) is a deadly disease in need of new therapeutic options. We recently developed a novel tricarbonylmethane agent (CMC2.24) as a therapeutic agent for PC, and evaluated its efficacy in preclinical models of PC. CMC2.24 inhibited the growth of various human PC cell lines in a conc...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Mallangada, Naveen A., Vargas, Joselin M., Thomas, Swaroopa, DiGiovanni, Matthew G., Vaeth, Brandon M., Nemesure, Matthew D., Wang, Ruixue, LaComb, Joseph F., Williams, Jennie L., Golub, Lorne M., Johnson, Francis, Mackenzie, Gerardo G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461215/
https://ncbi.nlm.nih.gov/pubmed/29683208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22830
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