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Prostate Cancer Stem Cell-Targeted Efficacy of a New-Generation Taxoid, SBT-1214 and Novel Polyenolic Zinc-Binding Curcuminoid, CMC2.24

BACKGROUND: Prostate cancer is the second leading cause of cancer death among men. Multiple evidence suggests that a population of tumor-initiating, or cancer stem cells (CSCs) is responsible for cancer development and exceptional drug resistance, representing a highly important therapeutic target....

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Main Authors: Botchkina, Galina I., Zuniga, Edison S., Rowehl, Rebecca H., Park, Rosa, Bhalla, Rahuldev, Bialkowska, Agnieszka B., Johnson, Francis, Golub, Lorne M., Zhang, Yu, Ojima, Iwao, Shroyer, Kenneth R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782470/
https://ncbi.nlm.nih.gov/pubmed/24086245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069884
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