Role of Src and Cortactin in Pemphigus Skin Blistering

Autoantibodies against desmoglein (Dsg) 1 and Dsg3 primarily cause blister formation in the autoimmune disease pemphigus vulgaris (PV). Src was proposed to contribute to loss of keratinocyte cohesion. However, the role and underlying mechanisms are unclear and were studied here. In keratinocytes, ce...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kugelmann, Daniela, Rötzer, Vera, Walter, Elias, Egu, Desalegn Tadesse, Fuchs, Michael Tobias, Vielmuth, Franziska, Vargas-Robles, Hilda, Schnoor, Michael, Hertl, Michael, Eming, Rüdiger, Rottner, Klemens, Schmidt, Ansgar, Spindler, Volker, Waschke, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461052/
https://ncbi.nlm.nih.gov/pubmed/31024527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00626
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