Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus

Pemphigus is an autoimmune blistering skin disease caused primarily by autoantibodies against desmoglein (Dsg)1 and 3. Here, we characterized the mechanisms engaged by pemphigus IgG from patients with different clinical phenotypes and autoantibody profiles. All pemphigus vulgaris (PV) and pemphigus...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Walter, Elias, Vielmuth, Franziska, Rotkopf, Lukas, Sárdy, Miklós, Horváth, Orsolya N., Goebeler, Matthias, Schmidt, Enno, Eming, Rüdiger, Hertl, Michael, Spindler, Volker, Waschke, Jens
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472593/
https://ncbi.nlm.nih.gov/pubmed/28620161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03697-7
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