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Dsg2 Upregulation as a Rescue Mechanism in Pemphigus

In pemphigus vulgaris (PV), autoantibodies directed against the desmosomal cadherin desmoglein (Dsg) 3 cause loss of intercellular adhesion. It is known that Dsg3 interactions are directly inhibited by autoantibody binding and that Dsg2 is upregulated in epidermis of PV patients. Here, we investigat...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Sigmund, Anna M., Steinert, Letyfee S., Egu, Desalegn T., Bayerbach, Franziska C., Waschke, Jens, Vielmuth, Franziska
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655986/
https://ncbi.nlm.nih.gov/pubmed/33193387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.581370
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