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Dsg2 Upregulation as a Rescue Mechanism in Pemphigus
In pemphigus vulgaris (PV), autoantibodies directed against the desmosomal cadherin desmoglein (Dsg) 3 cause loss of intercellular adhesion. It is known that Dsg3 interactions are directly inhibited by autoantibody binding and that Dsg2 is upregulated in epidermis of PV patients. Here, we investigat...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655986/ https://ncbi.nlm.nih.gov/pubmed/33193387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.581370 |
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