Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk

Epidermal infiltration of neutrophils is a hallmark of psoriasis, where their activation leads to release of neutrophil extracellular traps (NETs). The contribution of NETs to psoriasis pathogenesis has been unclear, but here we demonstrate that NETs drive inflammatory responses in skin through acti...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shao, Shuai, Fang, Hui, Dang, Erle, Xue, Ke, Zhang, Jieyu, Li, Bing, Qiao, Hongjiang, Cao, Tianyu, Zhuang, Yuchen, Shen, Shengxian, Zhang, Tongmei, Qiao, Pei, Li, Caixia, Gudjonsson, Johann E., Wang, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460719/
https://ncbi.nlm.nih.gov/pubmed/31024570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00746
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