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Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid
Bullous pemphigoid (BP) is an autoimmune bullous disease caused by autoantibodies against BP180 in the epidermal basement membrane. Autoantibody-mediated complement activation is an important process in BP pathogenesis. CD46, a crucial complement regulatory protein in the complement activation, has...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428046/ https://ncbi.nlm.nih.gov/pubmed/28273946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00235-3 |
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