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Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid

Bullous pemphigoid (BP) is an autoimmune bullous disease caused by autoantibodies against BP180 in the epidermal basement membrane. Autoantibody-mediated complement activation is an important process in BP pathogenesis. CD46, a crucial complement regulatory protein in the complement activation, has...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qiao, Pei, Dang, Erle, Cao, Tianyu, Fang, Hui, Zhang, Jieyu, Qiao, Hongjiang, Wang, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428046/
https://ncbi.nlm.nih.gov/pubmed/28273946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00235-3
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