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Enriched power of disease-concordant twin-case-only design in detecting interactions in genome-wide association studies
Genetic interaction is a crucial issue in the understanding of functional pathways underlying complex diseases. However, detecting such interaction effects is challenging in terms of both methodology and statistical power. We address this issue by introducing a disease-concordant twin-case-only desi...
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| 出版年: | Eur J Hum Genet |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6460588/ https://ncbi.nlm.nih.gov/pubmed/30659261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-018-0320-2 |
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