Enrichment of statistical power for genome-wide association studies

BACKGROUND: The inheritance of most human diseases and agriculturally important traits is controlled by many genes with small effects. Identifying these genes, while simultaneously controlling false positives, is challenging. Among available statistical methods, the mixed linear model (MLM) has been...

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Detalhes bibliográficos
Main Authors: Li, Meng, Liu, Xiaolei, Bradbury, Peter, Yu, Jianming, Zhang, Yuan-Ming, Todhunter, Rory J, Buckler, Edward S, Zhang, Zhiwu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210555/
https://ncbi.nlm.nih.gov/pubmed/25322753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0073-5
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