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ZP2 peptide beads select human sperm in vitro, decoy mouse sperm in vivo, and provide reversible contraception
Gamete recognition in the female reproductive tract occurs at the surface of the zona pellucida surrounding ovulated eggs. The acellular zona matrix is composed of three (mouse) or four (human) proteins (ZP1 to ZP4), and the amino terminus of ZP2 is the primary sperm-binding ligand. Mouse and human...
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| Published in: | Sci Transl Med |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6460476/ https://ncbi.nlm.nih.gov/pubmed/27122613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad9946 |
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