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A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans

The extracellular zona pellucida surrounds ovulated eggs and mediates gamete recognition that is essential for mammalian fertilization. Zonae matrices contain three (mouse) or four (human) glycoproteins (ZP1–4), but which protein binds sperm remains controversial. A defining characteristic of an ess...

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Détails bibliographiques
Auteurs principaux: Avella, Matteo A., Baibakov, Boris, Dean, Jurrien
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068139/
https://ncbi.nlm.nih.gov/pubmed/24934154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404025
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