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Human ZP4 is not sufficient for taxon-specific sperm recognition of the zona pellucida in transgenic mice

The molecular basis of human fertilization remains enigmatic. Mouse models are often used to study sperm–egg recognition, but the mouse zona pellucida surrounding ovulated eggs contains three proteins (ZP1, ZP2, and ZP3) whereas the human zona contains four (ZP1, ZP2, ZP3, and ZP4). Human sperm are...

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Detalhes bibliográficos
Main Authors: Yauger, Belinda, Boggs, Nathan A, Dean, Jurrien
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272266/
https://ncbi.nlm.nih.gov/pubmed/21173071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-10-0241
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