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Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis

Hutchinson–Gilford progeria syndrome (HGPS) is a rare pathology caused by a specific mutation (c.1824C>T; p.G608G) in the LMNA gene (Eriksson et al, 2003). In healthy conditions, LMNA encodes lamins A and C, two major structural nuclear proteins. The mutation creates a splice site in exon 11, res...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Di Pasquale, Elisa, Condorelli, Gianluigi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460347/
https://ncbi.nlm.nih.gov/pubmed/30902910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910360
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