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Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis
Hutchinson–Gilford progeria syndrome (HGPS) is a rare pathology caused by a specific mutation (c.1824C>T; p.G608G) in the LMNA gene (Eriksson et al, 2003). In healthy conditions, LMNA encodes lamins A and C, two major structural nuclear proteins. The mutation creates a splice site in exon 11, res...
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| Publicado no: | EMBO Mol Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6460347/ https://ncbi.nlm.nih.gov/pubmed/30902910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910360 |
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