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Spatial Clustering of Receptors and Signaling Molecules Regulates NK Cell Response to Peptide Repertoire Changes

Natural Killer (NK) cell activation requires integration of inhibitory and activating signaling. Inhibitory signals are determined by members of the killer cell immunoglobulin-like receptor (KIR) family, which have major histocompatibility complex (MHC) class I ligands. Loss of this inhibitory signa...

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Vydáno v:Front Immunol
Hlavní autoři: Mbiribindi, Berenice, Mukherjee, Sayak, Wellington, Dannielle, Das, Jayajit, Khakoo, Salim I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460049/
https://ncbi.nlm.nih.gov/pubmed/31024524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00605
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