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Spatial Clustering of Receptors and Signaling Molecules Regulates NK Cell Response to Peptide Repertoire Changes

Natural Killer (NK) cell activation requires integration of inhibitory and activating signaling. Inhibitory signals are determined by members of the killer cell immunoglobulin-like receptor (KIR) family, which have major histocompatibility complex (MHC) class I ligands. Loss of this inhibitory signa...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Mbiribindi, Berenice, Mukherjee, Sayak, Wellington, Dannielle, Das, Jayajit, Khakoo, Salim I.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460049/
https://ncbi.nlm.nih.gov/pubmed/31024524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00605
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