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Structural but Not Functional Alterations in Cones in the Absence of the Retinal Disease Protein Retinitis Pigmentosa 2 (RP2) in a Cone-Only Retina
X-linked retinitis pigmentosa 2 (XLRP2) patients and Rp2(null) mice exhibit severe cone photoreceptor degeneration. However, due to the paucity of cones in mammalian model systems, it is not clear how cones respond to the loss of RP2. Here we have used the Nrl(-/-) mice, which develop a rodless and...
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| Publié dans: | Front Genet |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6460013/ https://ncbi.nlm.nih.gov/pubmed/31024631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00323 |
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