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Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage

Neuroligins (NLGNs) are cell adhesion molecules located on the postsynaptic side of the synapse that interact with their presynaptic partners neurexins to maintain trans-synaptic connection. Fragile X syndrome (FXS) is a common neurodevelopmental disease that often co-occurs with autism and is cause...

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Publicat a:Mol Neurobiol
Autors principals: Chmielewska, Joanna J., Kuzniewska, Bozena, Milek, Jacek, Urbanska, Katarzyna, Dziembowska, Magdalena
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459971/
https://ncbi.nlm.nih.gov/pubmed/30056576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1243-1
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