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Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila
Neuroligins (Nlgs) are transmembrane cell adhesion molecules playing essential roles in synapse development and function. Genetic mutations in neuroligin genes have been linked with some neurodevelopmental disorders such as autism. These mutated Nlgs are mostly retained in the endoplasmic reticulum...
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| 出版年: | J Mol Cell Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5907836/ https://ncbi.nlm.nih.gov/pubmed/28498949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjx015 |
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