Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila

Neuroligins (Nlgs) are transmembrane cell adhesion molecules playing essential roles in synapse development and function. Genetic mutations in neuroligin genes have been linked with some neurodevelopmental disorders such as autism. These mutated Nlgs are mostly retained in the endoplasmic reticulum...

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Bibliografiske detaljer
Udgivet i:J Mol Cell Biol
Main Authors: Tu, Renjun, Qian, Jinjun, Rui, Menglong, Tao, Nana, Sun, Mingkuan, Zhuang, Yan, Lv, Huihui, Han, Junhai, Li, Moyi, Xie, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5907836/
https://ncbi.nlm.nih.gov/pubmed/28498949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjx015
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