The Fragile X Mental Retardation Protein Regulates Matrix Metalloproteinase 9 mRNA at Synapses

Activity-dependent protein synthesis at synapses is dysregulated in the Fragile X syndrome (FXS). This process contributes to dendritic spine dysmorphogenesis and synaptic dysfunction in FXS. Matrix Metalloproteinase 9 (MMP-9) is an enzyme involved in activity-dependent reorganization of dendritic s...

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Pubblicato in:J Neurosci
Autori principali: Janusz, Aleksandra, Miłek, Jacek, Perycz, Małgorzata, Pacini, Laura, Bagni, Claudia, Kaczmarek, Leszek, Dziembowska, Magdalena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619756/
https://ncbi.nlm.nih.gov/pubmed/24227732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2207-13.2013
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