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Specific protein 1(SP1) regulates the epithelial-mesenchymal transition via lysyl oxidase-like 2(LOXL2) in pancreatic ductal adenocarcinoma

Specific protein 1 (SP1) is associated with aggressive behavior, invasive clinical phenotype and poor clinical outcomes in various cancers. We studied whether SP1 exerts its effect on invasiveness and promotion of the epithelial-mesenchymal transition (EMT) by regulating lysyl oxidase-like 2 (LOXL2)...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kim, Im-kyung, Lee, Yun Sun, Kim, Hyung Sun, Dong, Seung Myung, Park, Joon Seong, Yoon, Dong Sup
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459819/
https://ncbi.nlm.nih.gov/pubmed/30976063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42501-6
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