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Still embedded together binding to membranes regulates Bcl-2 protein interactions

The dysregulation of apoptosis is a key step in developing tumours, and mediates resistance to cancer therapy. Many different signals for cell death converge on permeabilization of the outer mitochondrial membrane, which is controlled by the Bcl-2 family of proteins. The importance of this step is b...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Leber, B, Lin, J, Andrews, DW
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459407/
https://ncbi.nlm.nih.gov/pubmed/20639903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.283
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