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Mechanisms of Action of Bcl-2 Family Proteins

The Bcl-2 family of proteins controls a critical step in commitment to apoptosis by regulating permeabilization of the mitochondrial outer membrane (MOM). The family is divided into three classes: multiregion proapoptotic proteins that directly permeabilize the MOM; BH3 proteins that directly or ind...

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Detalhes bibliográficos
Main Authors: Shamas-Din, Aisha, Kale, Justin, Leber, Brian, Andrews, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683897/
https://ncbi.nlm.nih.gov/pubmed/23545417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a008714
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