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BCL-2 family proteins: changing partners in the dance towards death

The BCL-2 family of proteins controls cell death primarily by direct binding interactions that regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible release of intermembrane space proteins, subsequent caspase activation and apoptosis. The affinities and relative a...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Kale, Justin, Osterlund, Elizabeth J, Andrews, David W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729540/
https://ncbi.nlm.nih.gov/pubmed/29149100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.186
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