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BCL-2 family proteins: changing partners in the dance towards death

The BCL-2 family of proteins controls cell death primarily by direct binding interactions that regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible release of intermembrane space proteins, subsequent caspase activation and apoptosis. The affinities and relative a...

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Publicat a:Cell Death Differ
Autors principals: Kale, Justin, Osterlund, Elizabeth J, Andrews, David W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729540/
https://ncbi.nlm.nih.gov/pubmed/29149100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.186
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