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Fructose acutely stimulates NKCC2 activity in rat thick ascending limbs by increasing surface NKCC2 expression
The thick ascending limb (TAL) reabsorbs 25% of the filtered NaCl through the Na(+)-K(+)-2Cl(−) cotransporter (NKCC2). NKCC2 activity is directly related to surface NKCC2 expression and phosphorylation. Higher NaCl reabsorption by TALs is linked to salt-sensitive hypertension, which is linked to con...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6459307/ https://ncbi.nlm.nih.gov/pubmed/30516424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00136.2018 |
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