CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Longitudinal bone growth ceases with growth plate senescence during puberty. However, the molecular mechanisms of this phenomenon are largely unexplored. Here, we examined Wnt-responsive genes before and after growth plate senescence and found that CXXC finger protein 5 (CXXC5), a negative regulator...

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Bibliografske podrobnosti
izdano v:Life Sci Alliance
Main Authors: Choi, Sehee, Kim, Hyun-Yi, Cha, Pu-Hyeon, Seo, Seol Hwa, Lee, Chulho, Choi, Yejoo, Shin, Wookjin, Heo, Yunseok, Han, Gyoonhee, Lee, Weontae, Choi, Kang-Yell
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458850/
https://ncbi.nlm.nih.gov/pubmed/30971423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800254
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