CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Longitudinal bone growth ceases with growth plate senescence during puberty. However, the molecular mechanisms of this phenomenon are largely unexplored. Here, we examined Wnt-responsive genes before and after growth plate senescence and found that CXXC finger protein 5 (CXXC5), a negative regulator...

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Bibliografiske detaljer
Udgivet i:Life Sci Alliance
Main Authors: Choi, Sehee, Kim, Hyun-Yi, Cha, Pu-Hyeon, Seo, Seol Hwa, Lee, Chulho, Choi, Yejoo, Shin, Wookjin, Heo, Yunseok, Han, Gyoonhee, Lee, Weontae, Choi, Kang-Yell
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458850/
https://ncbi.nlm.nih.gov/pubmed/30971423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800254
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