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Strategies to overcome resistance to epidermal growth factor receptor monoclonal antibody therapy in metastatic colorectal cancer

Administration of monoclonal antibodies (mAbs) against epidermal growth factor receptor (EGFR) such as cetuximab and panitumumab in combination with conventional chemotherapy substantially prolongs survival of patients with metastatic colorectal cancer (mCRC). However, the efficacy of these mAbs is...

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Bibliografski detalji
Glavni autori: Jeong, Woo-Jeong, Cha, Pu-Hyeon, Choi, Kang-Yell
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123368/
https://ncbi.nlm.nih.gov/pubmed/25110417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i29.9862
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