Strategies to overcome resistance to epidermal growth factor receptor monoclonal antibody therapy in metastatic colorectal cancer

Administration of monoclonal antibodies (mAbs) against epidermal growth factor receptor (EGFR) such as cetuximab and panitumumab in combination with conventional chemotherapy substantially prolongs survival of patients with metastatic colorectal cancer (mCRC). However, the efficacy of these mAbs is...

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Bibliographic Details
Main Authors: Jeong, Woo-Jeong, Cha, Pu-Hyeon, Choi, Kang-Yell
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123368/
https://ncbi.nlm.nih.gov/pubmed/25110417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i29.9862
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