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Strategies to overcome resistance to epidermal growth factor receptor monoclonal antibody therapy in metastatic colorectal cancer

Administration of monoclonal antibodies (mAbs) against epidermal growth factor receptor (EGFR) such as cetuximab and panitumumab in combination with conventional chemotherapy substantially prolongs survival of patients with metastatic colorectal cancer (mCRC). However, the efficacy of these mAbs is...

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Bibliografiske detaljer
Main Authors: Jeong, Woo-Jeong, Cha, Pu-Hyeon, Choi, Kang-Yell
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123368/
https://ncbi.nlm.nih.gov/pubmed/25110417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i29.9862
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