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Strategies to overcome resistance to epidermal growth factor receptor monoclonal antibody therapy in metastatic colorectal cancer

Administration of monoclonal antibodies (mAbs) against epidermal growth factor receptor (EGFR) such as cetuximab and panitumumab in combination with conventional chemotherapy substantially prolongs survival of patients with metastatic colorectal cancer (mCRC). However, the efficacy of these mAbs is...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jeong, Woo-Jeong, Cha, Pu-Hyeon, Choi, Kang-Yell
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123368/
https://ncbi.nlm.nih.gov/pubmed/25110417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i29.9862
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